TY  - GEN
AU  - Subías Hidalgo, Marta
AU  - Yébenes, Hugo
AU  - Rodríguez-Gallego, César
AU  - Martín-Ambrosio, Adrián
AU  - Dominguez-Rodriguez, Mercedes
AU  - Tortajada, Agustin
AU  - Rodriguez de Cordoba, Santiago
AU  - Llorca Blanco, Oscar Antonio
PY  - 2017
DO  - 10.1002/eji.201646758
UR  - http://hdl.handle.net/20.500.12105/7168
AB  - C3 is the central component of the complement system. Upon activation, C3 sequentially generates various proteolytic fragments, C3a, C3b, iC3b, C3dg, each of them exposing novel surfaces, which are sites of interaction with other proteins. C3 and its...
LA  - eng
PB  - Wiley
KW  - C3
KW  - C3b
KW  - C3bBb convertase
KW  - Complement inhibition
KW  - Monoclonal antibody
KW  - Animals
KW  - Antibodies, Monoclonal
KW  - Antigen-Antibody Complex
KW  - Complement C3
KW  - Complement C3-C5 Convertases
KW  - Genetic Engineering
KW  - Hemolytic Plaque Technique
KW  - Humans
KW  - Hybridomas
KW  - Immunoglobulin Fab Fragments
KW  - Mice
KW  - Mice, Knockout
KW  - Protein Binding
KW  - Protein Conformation
KW  - Complement Pathway, Alternative
TI  - Functional and structural characterization of four mouse monoclonal antibodies to complement C3 with potential therapeutic and diagnostic applications
TY  - research article
ER  -