TY - GEN AU - Mas-Lloret, Vicente AU - Herfst, Sander AU - Osterhaus, Albert D M E AU - Fouchier, Ron A M AU - Melero, Jose Antonio PY - 2011 DO - 10.1128/JVI.05485-11 UR - http://hdl.handle.net/20.500.12105/17486 AB - The paramyxovirus F protein promotes fusion of the viral and cell membranes for virus entry, as well as cell-cell fusion for syncytium formation. Most paramyxovirus F proteins are triggered at neutral pH to initiate membrane fusion. Previous studies,... LA - eng PB - American Society for Microbiology (ASM) KW - Membrane Fusion KW - Virus Replication KW - Amino Acid Sequence KW - Animals KW - Cells, Cultured KW - Chlorocebus aethiops KW - Giant Cells KW - Histidine KW - Humans KW - Hydrogen-Ion Concentration KW - Kidney KW - Metapneumovirus KW - Models, Molecular KW - Molecular Sequence Data KW - Paramyxoviridae Infections KW - Phenotype KW - Protein Conformation KW - Sequence Homology, Amino Acid KW - Vero Cells KW - Viral Fusion Proteins TI - Residues of the human metapneumovirus fusion (F) protein critical for its strain-related fusion phenotype: implications for the virus replication cycle TY - research article ER -