TY - JOUR AU - Manieri, Elisa AU - Folgueira, Cintia AU - Rodríguez, María Elena AU - Leiva-Vega, Luis AU - Esteban-Lafuente, Laura AU - Chen, Chaobo AU - Cubero, Francisco Javier AU - Barrett, Tamera AU - Cavanagh-Kyros, Julie AU - Seruggia, Davide AU - Rosell, Alejandro AU - Sanchez-Cabo, Fatima AU - Gomez, Manuel J AU - Monte, Maria J AU - G Marin, Jose J AU - Davis, Roger J AU - Mora, Alfonso AU - Sabio, Guadalupe PY - 2020 DO - 10.1073/pnas.2002672117 SN - 0027-8424 UR - http://hdl.handle.net/20.500.12105/11239 AB - Metabolic stress causes activation of the cJun NH2-terminal kinase (JNK) signal transduction pathway. It is established that one consequence of JNK activation is the development of insulin resistance and hepatic steatosis through inhibition of the... LA - eng PB - National Academy of Sciences KW - Animals TI - JNK-mediated disruption of bile acid homeostasis promotes intrahepatic cholangiocarcinoma. TY - journal article ER -