TY - JOUR AU - Vilas, Jéssica M AU - Ferreirós, Alba AU - Carneiro, Carmen AU - Morey, Lluis AU - Da Silva-Álvarez, Sabela AU - Fernandes, Tânia AU - Di Croce, Luciano AU - García-Caballero, Tomás AU - Rivas, Carmen AU - Vidal, Anxo AU - Serrano Marugan, Manuel PY - 2015 DO - 10.18632/oncotarget.2996 UR - http://hdl.handle.net/20.500.12105/10360 AB - Cellular reprogramming to iPSCs has uncovered unsuspected links between tumor suppressors and pluripotency factors. Using this system, it was possible to identify tumor suppressor p27 as a repressor of Sox2 during differentiation. This led to the... LA - eng PB - Impact Journals KW - IPS CELLS KW - RB FAMILY KW - STEM KW - SUPPRESSION KW - PATHWAY KW - MOUSE KW - GENE KW - MECHANISMS KW - MICE KW - Transcription, Genetic KW - Animals KW - Cellular Reprogramming KW - Epigenesis, Genetic KW - Gene Expression Regulation, Developmental KW - Gene Expression Regulation, Neoplastic KW - Genotype KW - HEK293 Cells KW - Humans KW - Induced Pluripotent Stem Cells KW - Mice, 129 Strain KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Neoplastic Stem Cells KW - Phenotype KW - Pituitary Neoplasms KW - RNA Interference KW - Retinoblastoma Protein KW - Retinoblastoma-Like Protein p107 KW - Retinoblastoma-Like Protein p130 KW - SOXB1 Transcription Factors KW - Transfection KW - Tumor Suppressor Protein p53 TI - Transcriptional regulation of Sox2 by the retinoblastoma family of pocket proteins. TY - journal article ER -