TY  - JOUR
AU  - Tummala, Krishna S
AU  - Brandt, Marta
AU  - Teijeiro, Ana
AU  - Graña Castro, Osvaldo
AU  - Schwabe, Robert F
AU  - Perna, Cristian
AU  - Djouder, Nabil
PY  - 2017
DO  - 10.1016/j.celrep.2017.03.059
SN  - 22111247
UR  - http://hdl.handle.net/20.500.12105/7231
AB  - Hepatocellular carcinoma (HCC) is an aggressive primary liver cancer. However, its origin remains a debated question. Using human data and various hepatocarcinogenesis mouse models, we show that, in early stages, transformed hepatocytes, independent...
LA  - eng
PB  - Elsevier
KW  - DNA damage
KW  - HCC
KW  - NAD(+)
KW  - Adenomas
KW  - Galectin-3
KW  - Hepatic progenitor cells
KW  - Hepatocytes
KW  - Lineage tracking
KW  - Regenerative nodules
KW  - α-ketoglutarate
KW  - Animals
KW  - Carcinogenesis
KW  - Carcinoma, Hepatocellular
KW  - Cell Differentiation
KW  - Galectin 3
KW  - Hepatocytes
KW  - Humans
KW  - Ketoglutaric Acids
KW  - Liver Neoplasms
KW  - Mice, Transgenic
KW  - Neoplasm Invasiveness
KW  - Stem Cells
TI  - Hepatocellular Carcinomas Originate Predominantly from Hepatocytes and Benign Lesions from Hepatic Progenitor Cells
TY  - journal article
ER  -