TY - JOUR AU - Molina, Ester AU - García-Gutiérrez, Lucía AU - Junco, Vanessa AU - Perez-Olivares, Mercedes AU - de Yébenes, Virginia G AU - Blanco, Rosa AU - Quevedo, Laura AU - Acosta, Juan C AU - Marín, Ana V AU - Ulgiati, Daniela AU - Merino, Ramon AU - Delgado, M Dolores AU - Varela, Ignacio AU - Regueiro, José R AU - Moreno de Alborán, Ignacio AU - Ramiro, Almudena R AU - León, Javier PY - 2023 DO - 10.1038/s41388-023-02846-9 UR - http://hdl.handle.net/20.500.12105/16764 AB - MYC is an oncogenic transcription factor dysregulated in about half of total human tumors. While transcriptomic studies reveal more than 1000 genes regulated by MYC, a much smaller fraction of genes is directly transactivated by MYC. Virtually all... LA - eng PB - Springer KW - Burkitt Lymphoma KW - Epstein-Barr Virus Infections KW - Animals KW - Humans KW - Mice KW - B-Lymphocytes KW - Genes, myc KW - Herpesvirus 4, Human TI - MYC directly transactivates CR2/CD21, the receptor of the Epstein-Barr virus, enhancing the viral infection of Burkitt lymphoma cells. TY - journal article ER -