TY - GEN AU - Casanova-Acebes, Maria AU - Dalla, Erica AU - Leader, Andrew M AU - LeBerichel, Jessica AU - Nikolic, Jovan AU - Morales, Blanca M AU - Brown, Markus AU - Chang, Christie AU - Troncoso, Leanna AU - Chen, Steven T AU - Sastre-Perona, Ana AU - Park, Matthew D AU - Tabachnikova, Alexandra AU - Dhainaut, Maxime AU - Hamon, Pauline AU - Maier, Barbara AU - Sawai, Catherine M AU - Agulló-Pascual, Esperanza AU - Schober, Markus AU - Brown, Brian D AU - Reizis, Boris AU - Marron, Thomas AU - Kenigsberg, Ephraim AU - Moussion, Christine AU - Benaroch, Philippe AU - Aguirre-Ghiso, Julio A AU - Merad, Miriam PY - 2021 UR - https://hdl.handle.net/20.500.12105/27263 AB - Macrophages have a key role in shaping the tumour microenvironment (TME), tumour immunity and response to immunotherapy, which makes them an important target for cancer treatment. However, modulating macrophages has proved extremely difficult, as we... LA - eng PB - NATURE PORTFOLIO KW - EPITHELIAL-MESENCHYMAL TRANSITIONS KW - REGULATORY T-CELLS KW - STEM CELLS KW - EMT KW - DIFFERENTIATION KW - MONOCYTE KW - ACCUMULATION KW - PLATFORM KW - REVEALS KW - MODELS TI - Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells. TY - research article ER -