TY - GEN AU - Takaoka, Minoru AU - Tadross, John A AU - Al-Hadithi, Ali B A K AU - Zhao, Xiaohui AU - Villena-Gutiérrez, Rocío AU - Tromp, Jasper AU - Absar, Shazia AU - Au, Marcus AU - Harrison, James AU - Coll, Anthony P AU - Marciniak, Stefan J AU - Rimmington, Debra AU - Oliver, Eduardo AU - Ibáñez, Borja AU - Voors, Adriaan A AU - O'Rahilly, Stephen AU - Mallat, Ziad AU - Goodall, Jane C PY - 2024 UR - https://hdl.handle.net/20.500.12105/26541 AB - Heart failure and associated cachexia is an unresolved and important problem. This study aimed to determine the factors that contribute to cardiac cachexia in a new model of heart failure in mice that lack the integrated stress response (ISR) induced... LA - eng PB - Oxford University Press KW - Cachexia KW - GDF15 KW - Heart failure KW - Integrated stress response KW - PPP1R15A TI - GDF15 antagonism limits severe heart failure and prevents cardiac cachexia. TY - research article ER -