TY  - JOUR
AU  - Cueto, Francisco J
AU  - Del Fresno, Carlos
AU  - Brandi, Paola
AU  - Combes, Alexis J
AU  - Hernández-García, Elena
AU  - Sánchez-Paulete, Alfonso R
AU  - Enamorado, Michel
AU  - Bromley, Christian P
AU  - Gomez, Manuel J
AU  - Conde-Garrosa, Ruth
AU  - Mañes, Santos
AU  - Zelenay, Santiago
AU  - Melero, Ignacio
AU  - Iborra, Salvador
AU  - Krummel, Matthew F
AU  - Sancho, David
PY  - 2021
DO  - 10.1136/jitc-2020-002054
UR  - http://hdl.handle.net/20.500.12105/15091
AB  - Conventional type 1 dendritic cells (cDC1s) are central to antitumor immunity and their presence in the tumor microenvironment associates with improved outcomes in patients with cancer. DNGR-1 (CLEC9A) is a dead cell-sensing receptor highly restricted...
LA  - eng
PB  - BMJ Publishing Group
KW  - Genetic Therapy
KW  - Animals
KW  - Basic-Leucine Zipper Transcription Factors
KW  - CD8-Positive T-Lymphocytes
KW  - Cell Line, Tumor
KW  - Chemokine CCL5
KW  - Coculture Techniques
KW  - Colonic Neoplasms
KW  - Dendritic Cells
KW  - Gene Expression Regulation, Neoplastic
KW  - Lectins, C-Type
KW  - Lymphocytes, Tumor-Infiltrating
KW  - Melanoma, Experimental
KW  - Membrane Proteins
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - Phenotype
KW  - Receptors, CCR5
KW  - Receptors, Immunologic
KW  - Repressor Proteins
KW  - Signal Transduction
KW  - Skin Neoplasms
KW  - Tumor Burden
KW  - Tumor Escape
KW  - Tumor Microenvironment
TI  - DNGR-1 limits Flt3L-mediated antitumor immunity by restraining tumor-infiltrating type I conventional dendritic cells.
TY  - journal article
ER  -