TY - GEN AU - Calvete, Oriol AU - Garcia-Pavia, Pablo AU - Dominguez, Fernando AU - Mosteiro, Lluc AU - Pérez-Cabornero, Lucía AU - Cantalapiedra, Diego AU - Zorio, Esther AU - Ramón Y Cajal, Teresa AU - Crespo-Leiro, Maria G AU - Teulé, Álex AU - Lázaro, Conxi AU - Morente, Manuel M AU - Urioste, Miguel AU - Benitez, Javier PY - 2019 DO - 10.1161/JAHA.119.012875 SN - 2047-9980 UR - http://hdl.handle.net/20.500.12105/8375 AB - Background Mutations in the POT1 gene explain abnormally long telomeres and multiple tumors including cardiac angiosarcomas (CAS). However, the link between long telomeres and tumorigenesis is poorly understood. Methods and Results Here, we have... LA - eng PB - American Heart Association (AHA) KW - POT1 KW - VEGF/angiogenesis pathway KW - Cardiac angiosarcoma KW - Cell cycle arrest KW - Damage response TI - POT1 and Damage Response Malfunction Trigger Acquisition of Somatic Activating Mutations in the VEGF Pathway in Cardiac Angiosarcomas TY - research article ER -