TY - JOUR AU - Fuster, Jose J. AU - Zuriaga, MarĂ­a A AU - Ngo, Doan Thi-Minh AU - Farb, Melissa G AU - Aprahamian, Tamar AU - Yamaguchi, Terry P AU - Gokce, Noyan AU - Walsh, Kenneth PY - 2015 DO - 10.2337/db14-1164 UR - http://hdl.handle.net/20.500.12105/17483 AB - Adipose tissue dysfunction plays a pivotal role in the development of insulin resistance in obese individuals. Cell culture studies and gain-of-function mouse models suggest that canonical Wnt proteins modulate adipose tissue expansion. However, no... LA - eng PB - American Diabetes Association (ADA) KW - Animals KW - Glucose KW - Humans KW - Inflammation KW - Insulin Resistance KW - Intra-Abdominal Fat KW - Macrophages KW - Mice KW - Obesity KW - Phosphorylation KW - Subcutaneous Fat KW - Wnt Signaling Pathway TI - Noncanonical Wnt signaling promotes obesity-induced adipose tissue inflammation and metabolic dysfunction independent of adipose tissue expansion. TY - journal article ER -