TY - GEN AU - Brandi, Jessica AU - Cecconi, Daniela AU - Cordani, Marco AU - Torrens-Mas, Margalida AU - Pacchiana, Raffaella AU - Dalla Pozza, Elisa AU - Butera, Giovanna AU - Manfredi, Marcello AU - Marengo, Emilio AU - Oliver, Jordi AU - Roca, Pilar AU - Dando, Ilaria AU - Donadelli, Massimo PY - 2016 DO - 10.1016/j.freeradbiomed.2016.10.499 UR - http://hdl.handle.net/20.500.12105/20217 AB - Several evidence indicate that metabolic alterations play a pivotal role in cancer development. Here, we report that the mitochondrial uncoupling protein 2 (UCP2) sustains the metabolic shift from mitochondrial oxidative phosphorylation (mtOXPHOS) to... LA - eng PB - Elsevier KW - Deoxyglucose KW - Insulin-Secreting Cells KW - Mitochondria KW - Reactive Oxygen Species KW - Glycolysis KW - Humans KW - Cell Line, Tumor KW - Acetylcysteine KW - Carrier Proteins KW - Cell Proliferation KW - Membrane Proteins KW - RNA, Small Interfering KW - Thyroid Hormones KW - L-Lactate Dehydrogenase KW - Gene Expression Profiling KW - Glucose Transporter Type 1 KW - Heterogeneous-Nuclear Ribonucleoprotein Group A-B KW - Uncoupling Protein 2 KW - Signal Transduction KW - Oxidative Phosphorylation KW - RNA, Messenger KW - Iridoids KW - Gene Expression Regulation, Neoplastic TI - The antioxidant uncoupling protein 2 stimulates hnRNPA2/B1, GLUT1 and PKM2 expression and sensitizes pancreas cancer cells to glycolysis inhibition TY - research article ER -