TY - JOUR AU - Rodríguez-Izquierdo, Ignacio AU - Sepulveda-Crespo, Daniel AU - Lasso, Jose María AU - Resino, Salvador AU - Muñoz-Fernández, María Ángeles PY - 2022 DO - 10.1002/wnan.1774 UR - http://hdl.handle.net/20.500.12105/14552 AB - Although a wide variety of topical microbicides provide promising in vitro and in vivo efficacy, most of them failed to prevent sexual transmission of human immunodeficiency virus type 1 (HIV-1) in human clinical trials. In vitro, ex vivo, and in vivo... LA - eng PB - Wiley KW - HIV-1 KW - Acceptability KW - Dendrimer KW - Preclinical steps KW - Regulation KW - Vaginal microbicide TI - Baseline and time-updated factors in preclinical development of anionic dendrimers as successful anti-HIV-1 vaginal microbicides TY - journal article ER -