TY - GEN AU - Aterido, Adrià AU - Cañete, Juan D AU - Tornero, Jesús AU - Blanco, Francisco AU - Fernández-Gutierrez, Benjamín AU - Pérez, Carolina AU - Alperi-López, Mercedes AU - Olivè, Alex AU - Corominas, Héctor AU - Martínez-Taboada, Víctor AU - González, Isidoro AU - Fernández-Nebro, Antonio AU - Erra, Alba AU - López-Lasanta, María AU - López Corbeto, Mireia AU - Palau, Núria AU - Marsal, Sara AU - Julià, Antonio PY - 2019 DO - 10.3389/fimmu.2019.01459 UR - http://hdl.handle.net/20.500.12105/17885 AB - Background: Rheumatoid arthritis (RA) is the most frequent autoimmune disease involving the joints. Although anti-TNF therapies have proven effective in the management of RA, approximately one third of patients do not show a significant clinical... LA - eng KW - anti-TNF therapy KW - Genomics KW - Multi-omics association analysis KW - Rheumatoid arthritis KW - Transcriptomics KW - Adalimumab KW - Antirheumatic Agents KW - Arthritis, Rheumatoid KW - Biopsy KW - Cohort Studies KW - Female KW - Gene Regulatory Networks KW - Genome-Wide Association Study KW - Humans KW - Infliximab KW - Male KW - Polymorphism, Single Nucleotide KW - Synovial Membrane KW - Transcriptome KW - Treatment Outcome KW - Tumor Necrosis Factor-alpha TI - A Combined Transcriptomic and Genomic Analysis Identifies a Gene Signature Associated With the Response to Anti-TNF Therapy in Rheumatoid Arthritis TY - research article ER -