TY  - JOUR
AU  - Pernaute, Barbara
AU  - Spruce, Thomas
AU  - Smith, Kimberley M
AU  - Sánchez-Nieto, Juan Miguel
AU  - Manzanares, Miguel
AU  - Cobb, Bradley
AU  - Rodríguez, Tristan A
PY  - 2014
DO  - 10.1101/gad.245621.114
SN  - 0890-9369
UR  - http://hdl.handle.net/20.500.12105/7353
AB  - Mammalian primed pluripotent stem cells have been shown to be highly susceptible to cell death stimuli due to their low apoptotic threshold, but how this threshold is regulated remains largely unknown. Here we identify microRNA (miRNA)-mediated...
LA  - eng
PB  - Cold Spring Harbor Laboratory Press
KW  - Bim
KW  - Dicer
KW  - Apoptosis
KW  - Epiblast
KW  - microRNAs
KW  - Pluripotency
KW  - Animals
KW  - Apoptosis
KW  - Apoptosis Regulatory Proteins
KW  - Bcl-2-Like Protein 11
KW  - Cell Survival
KW  - Cells, Cultured
KW  - Gene Expression Profiling
KW  - Membrane Proteins
KW  - Mice
KW  - MicroRNAs
KW  - Mitochondria
KW  - Pluripotent Stem Cells
KW  - Proto-Oncogene Proteins
KW  - Gene Expression Regulation, Developmental
TI  - MicroRNAs control the apoptotic threshold in primed pluripotent stem cells through regulation of BIM
TY  - journal article
ER  -