TY - GEN AU - Ariza, Adriana AU - Collado, Daniel AU - Vida, Yolanda AU - Montañez, María I AU - Pérez-Inestrosa, Ezequiel AU - Blanca, Miguel AU - Torres, María José AU - Cañada, F Javier AU - Pérez-Sala, Dolores PY - 2014 DO - 10.1371/journal.pone.0090891 UR - http://hdl.handle.net/20.500.12105/17060 AB - Allergic reactions towards β-lactam antibiotics pose an important clinical problem. The ability of small molecules, such as a β-lactams, to bind covalently to proteins, in a process known as haptenation, is considered necessary for induction of a... LA - eng PB - Public Library of Science (PLOS) KW - Animales KW - Antibacterianos KW - Biotinilación KW - Butilaminas KW - Haptenos KW - Hipersensibilidad KW - Amoxicilina KW - Inmunoglobulina E KW - Macrófagos KW - Estructura molecular KW - Beta-lactamas KW - Animals KW - Anti-Bacterial Agents KW - Binding, Competitive KW - Biotinylation KW - Butylamines KW - Haptens KW - Humans KW - Hypersensitivity KW - Immunoglobulin E KW - Macrophages KW - Mice KW - Microscopy, Confocal KW - Molecular Structure KW - Serum Albumin KW - beta-Lactams KW - Amoxicillin TI - Study of protein haptenation by amoxicillin through the use of a biotinylated antibiotic. TY - research article ER -