TY  - JOUR
AU  - Sanz-Castillo, Belén
AU  - Hurtado, Begoña
AU  - Vara-Ciruelos, Diana
AU  - El Bakkali, Aicha
AU  - Hermida, Dario
AU  - Salvador-Barbero, Beatriz
AU  - Martínez-Alonso, Diego
AU  - González-Martínez, José
AU  - Santiveri, Clara
AU  - Campos Olivas, Ramon
AU  - Ximénez-Embún, Pilar
AU  - Muñoz, Javier
AU  - Álvarez-Fernández, Mónica
AU  - Malumbres, Marcos
PY  - 2023
DO  - 10.15252/embj.2022110833
UR  - http://hdl.handle.net/20.500.12105/18963
AB  - The AKT-mTOR pathway is a central regulator of cell growth and metabolism. Upon sustained mTOR activity, AKT activity is attenuated by a feedback loop that restrains upstream signaling. However, how cells control the signals that limit AKT activity is...
LA  - eng
PB  - Wiley
KW  - Mechanistic Target of Rapamycin Complex 1
KW  - Protein Phosphatase 2
KW  - Protein Serine-Threonine Kinases
KW  - Animals
KW  - Mice
KW  - Cell Cycle
KW  - Glucose
KW  - Mitosis
KW  - Phosphatidylinositol 3-Kinases
KW  - Phosphorylation
KW  - Proto-Oncogene Proteins c-akt
TI  - The MASTL/PP2A cell cycle kinase-phosphatase module restrains PI3K-Akt activity in an mTORC1-dependent manner.
TY  - journal article
ER  -