TY  - JOUR
AU  - de la Calle Arregui, Celia
AU  - Plata-Gómez, Ana Belén
AU  - Deleyto-Seldas, Nerea
AU  - García, Fernando
AU  - Ortega-Molina, Ana
AU  - Abril-Garrido, Julio
AU  - Rodriguez, Elena
AU  - Nemazanyy, Ivan
AU  - Tribouillard, Laura
AU  - de Martino, Alba
AU  - Caleiras, Eduardo
AU  - Laplante, Mathieu
AU  - Muñoz, Javier
AU  - Pende, Mario
AU  - Sabio, Guadalupe
AU  - Sabatini, David M
AU  - Efeyan, Alejo
AU  - Mulero, Francisca
AU  - Campos Olivas, Ramon
PY  - 2021
DO  - 10.1038/s41467-021-23857-8
UR  - http://hdl.handle.net/20.500.12105/13734
AB  - The mechanistic target of rapamycin complex 1 (mTORC1) integrates cellular nutrient signaling and hormonal cues to control metabolism. We have previously shown that constitutive nutrient signaling to mTORC1 by means of genetic activation of RagA...
LA  - eng
PB  - Nature Publishing Group
KW  - MTORC1
KW  - REVEALS
KW  - LIVER
KW  - MODEL
KW  - Signal Transduction
KW  - Animals
KW  - Disease Models, Animal
KW  - Fasting
KW  - Glucose
KW  - Homeostasis
KW  - Humans
KW  - Liver
KW  - Mechanistic Target of Rapamycin Complex 1
KW  - Mice
KW  - Monomeric GTP-Binding Proteins
KW  - Nutrients
KW  - PPAR alpha
KW  - Phenotype
KW  - Proteomics
KW  - Sirolimus
KW  - Transcription, Genetic
KW  - Tuberous Sclerosis Complex 1 Protein
TI  - Limited survival and impaired hepatic fasting metabolism in mice with constitutive Rag GTPase signaling.
TY  - journal article
ER  -