TY  - JOUR
AU  - Zong, Dali
AU  - Adam, Salomé
AU  - Wang, Yifan
AU  - Sasanuma, Hiroyuki
AU  - Callén, Elsa
AU  - Murga, Matilde
AU  - Day, Amanda
AU  - Kruhlak, Michael J
AU  - Wong, Nancy
AU  - Munro, Meagan
AU  - Ray Chaudhuri, Arnab
AU  - Karim, Baktiar
AU  - Xia, Bing
AU  - Takeda, Shunichi
AU  - Johnson, Neil
AU  - Durocher, Daniel
AU  - Nussenzweig, André
PY  - 2019
DO  - 10.1016/j.molcel.2018.12.010
UR  - http://hdl.handle.net/20.500.12105/17692
AB  - BRCA1 functions at two distinct steps during homologous recombination (HR). Initially, it promotes DNA end resection, and subsequently it recruits the PALB2 and BRCA2 mediator complex, which stabilizes RAD51-DNA nucleoprotein filaments. Loss of 53BP1...
LA  - eng
PB  - Cell Press
KW  - Haploinsufficiency
KW  - Ubiquitination
KW  - Animals
KW  - BRCA1 Protein
KW  - BRCA2 Protein
KW  - Cell Line, Tumor
KW  - Chromatin
KW  - DNA Damage
KW  - Fanconi Anemia Complementation Group N Protein
KW  - Female
KW  - Fibroblasts
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - Mutation
KW  - Neoplasms
KW  - Poly(ADP-ribose) Polymerase Inhibitors
KW  - Rad51 Recombinase
KW  - Recombinational DNA Repair
KW  - Tumor Suppressor p53-Binding Protein 1
KW  - Ubiquitin-Protein Ligases
TI  - BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation.
TY  - journal article
ER  -