TY  - GEN
AU  - Oliva-Martinez, Jose Luis
AU  - Zarich-Dimitrievich, Natasha
AU  - Martinez, Natalia
AU  - Jorge, Rocío
AU  - Castrillo, Antonio
AU  - Azañedo, Marta
AU  - Garcia-Vargas, Susana
AU  - Gutiérrez-Eisman, Silvia
AU  - Juarranz, Angeles
AU  - Boscá, Lisardo
AU  - Gutkind, J Silvio
AU  - Rojas-Cabañeros, Jose Maria
PY  - 2004
DO  - 10.1074/jbc.M404058200
SN  - 0021-9258
UR  - http://hdl.handle.net/20.500.12105/9698
AB  - Ras proteins (H-, N-, and K-Ras) operate as molecular switches in signal transduction cascades controlling cell proliferation, differentiation, or apoptosis. The interaction of Ras with its effectors is mediated by the effector-binding loop, but...
LA  - eng
PB  - American Society for Biochemistry and Molecular Biology (ASBMB)
KW  - Animals
KW  - Binding Sites
KW  - DNA-Binding Proteins
KW  - Enzyme Activation
KW  - Gene Expression
KW  - Genes, ras
KW  - Humans
KW  - Mice
KW  - Mitogen-Activated Protein Kinase 1
KW  - Mitogen-Activated Protein Kinase 3
KW  - Mitogen-Activated Protein Kinases
KW  - NIH 3T3 Cells
KW  - Phosphatidylinositol 3-Kinases
KW  - Phospholipase D
KW  - Protein Isoforms
KW  - Protein-Serine-Threonine Kinases
KW  - Proto-Oncogene Proteins
KW  - Proto-Oncogene Proteins c-akt
KW  - Proto-Oncogene Proteins c-raf
KW  - Signal Transduction
KW  - Structure-Activity Relationship
KW  - Transcription Factors
KW  - Transfection
KW  - ets-Domain Protein Elk-1
KW  - rac1 GTP-Binding Protein
KW  - ral GTP-Binding Proteins
KW  - ral Guanine Nucleotide Exchange Factor
KW  - ras Proteins
KW  - Mutation
TI  - The P34G mutation reduces the transforming activity of K-Ras and N-Ras in NIH 3T3 cells but not of H-Ras
TY  - research article
ER  -