TY - GEN AU - Álvarez-Fernández, Carmen AU - Crespo Guardo, Alberto AU - García-Pérez, Javier AU - García, Felipe AU - Blanco, Julia AU - Escribà-García, Laura AU - Gatell, José María AU - Alcamí, José AU - Plana, Montserrat AU - Sánchez-Palomino, Sonsoles PY - 2012 DO - 10.1371/journal.pone.0048848 SN - 1932-6203 UR - http://hdl.handle.net/20.500.12105/7115 AB - BACKGROUND: The generation of new immunogens able to elicit strong specific immune responses remains a major challenge in the attempts to obtain a prophylactic or therapeutic vaccine against HIV/AIDS. We designed and constructed a defective... LA - eng PB - Public Library of Science (PLOS) KW - AIDS Vaccines KW - Cohort Studies KW - HEK293 Cells KW - HIV Reverse Transcriptase KW - HIV Seropositivity KW - HIV-1 KW - Humans KW - Immunity, Cellular KW - Interferon-gamma KW - Sequence Deletion KW - Virion KW - Virus Replication TI - Generation and characterization of a defective HIV-1 Virus as an immunogen for a therapeutic vaccine TY - research article ER -