TY - JOUR AU - Neri, Tui AU - Hiriart, Emilye AU - van Vliet, Patrick P AU - Faure, Emilie AU - Norris, Russell A AU - Farhat, Batoul AU - Jagla, Bernd AU - Lefrancois, Julie AU - Sugi, Yukiko AU - Moore-Morris, Thomas AU - Zaffran, Stéphane AU - Faustino, Randolph S AU - Zambon, Alexander C AU - Desvignes, Jean-Pierre AU - Salgado, David AU - Levine, Robert A AU - de la Pompa, Jose Luis AU - Terzic, André AU - Evans, Sylvia M AU - Markwald, Roger AU - Pucéat, Michel PY - 2019 DO - 10.1038/s41467-019-09459-5 SN - 2041-1723 UR - http://hdl.handle.net/20.500.12105/7541 AB - Genetically modified mice have advanced our understanding of valve development and disease. Yet, human pathophysiological valvulogenesis remains poorly understood. Here we report that, by combining single cell sequencing and in vivo approaches, a... LA - eng PB - Nature Publishing Group TI - Human pre-valvular endocardial cells derived from pluripotent stem cells recapitulate cardiac pathophysiological valvulogenesis TY - journal article ER -