TY - JOUR AU - Humbert, Nicolas AU - Navaratnam, Naveenan AU - Augert, Arnaud AU - Da Costa, Marco AU - Martien, Sébastien AU - Wang, Jing AU - Martinez Garcia, Maria Dolores AU - Abbadie, Corinne AU - Carling, David AU - de Launoit, Yvan AU - Gil, Jesús AU - Bernard, David PY - 2010 DO - 10.1038/emboj.2009.342 UR - http://hdl.handle.net/20.500.12105/17412 AB - Senescence is an irreversible cell-cycle arrest that is elicited by a wide range of factors, including replicative exhaustion. Emerging evidences suggest that cellular senescence contributes to ageing and acts as a tumour suppressor mechanism. To... LA - eng PB - EMBO Press KW - Cellular Senescence KW - Ploidies KW - AMP-Activated Protein Kinase Kinases KW - Cell Line KW - Fibroblasts KW - Gene Expression Regulation KW - Humans KW - Phosphorylation KW - Protein Kinases KW - Protein Serine-Threonine Kinases KW - Repressor Proteins TI - Regulation of ploidy and senescence by the AMPK-related kinase NUAK1. TY - journal article ER -