TY - GEN AU - Ruiz-de-León, María J AU - Jimenez-Sousa, Maria Angeles AU - Moreno, Santiago AU - García, Marcial AU - Gutiirrez-Rivas, Monica AU - León, Agathe AU - Montero-Alonso, Marta AU - González-García, Juan AU - Resino, Salvador AU - Rallón, Norma AU - Benito, José Miguel AU - Vallejo, Alejandro AU - ECRIS Network integrated in the Spanish AIDS Research Network AU - Briz, Veronica AU - Vázquez-Morón, Sonia AU - Fernández, A AU - García, P AU - Pernas, Maria AU - Casado, Concepcion AU - López, C AU - Capa, Laura AU - Pérez, M AU - Alcamí, José PY - 2019 DO - 10.1016/j.jmii.2018.07.007 UR - http://hdl.handle.net/20.500.12105/12456 AB - Exosome-derived miR-21 was independently associated with CD4 T cell decline in HIV-1-infected elite controllers (OR 0.369, 95% CI 0.137-0.994, p = 0.049). Also, a negative correlation between miR-21 expression and MCP-1 level was found (r = -0.649,... LA - eng PB - Elsevier KW - Exosomes KW - miRNAs KW - HIV-1 KW - Elite controllers KW - Immune activation KW - Soluble biomarkers KW - Exosomes KW - Adult KW - Biomarkers KW - CD4 Lymphocyte Count KW - CD4-Positive T-Lymphocytes KW - Chemokine CCL2 KW - Cross-Sectional Studies KW - Female KW - HIV Infections KW - HIV-1 KW - Humans KW - Male KW - MicroRNAs KW - Middle Aged KW - Plasma TI - Lower expression of plasma-derived exosome miR-21 levels in HIV-1 elite controllers with decreasing CD4 T cell count TY - research article ER -