TY  - GEN
AU  - Li, Jing
AU  - Ohmura, Shunya
AU  - Marchetto, Aruna
AU  - Orth, Martin F
AU  - Imle, Roland
AU  - Dallmayer, Marlene
AU  - Musa, Julian
AU  - Knott, Maximilian M L
AU  - Hölting, Tilman L B
AU  - Stein, Stefanie
AU  - Funk, Cornelius M
AU  - Sastre, Ana
AU  - Alonso, Javier
AU  - Bestvater, Felix
AU  - Kasan, Merve
AU  - Romero-Pérez, Laura
AU  - Hartmann, Wolfgang
AU  - Ranft, Andreas
AU  - Banito, Ana
AU  - Dirksen, Uta
AU  - Kirchner, Thomas
AU  - Cidre-Aranaz, Florencia
AU  - Grünewald, Thomas G P
PY  - 2021
DO  - 10.1038/s41467-021-25553-z
UR  - http://hdl.handle.net/20.500.12105/13427
AB  - Chromosomal instability (CIN) is a hallmark of cancer1. Yet, many childhood cancers, such as Ewing sarcoma (EwS), feature remarkably 'silent' genomes with minimal CIN2. Here, we show in the EwS model how uncoupling of mitosis and cytokinesis via...
LA  - eng
PB  - Nature Publishing Group
TI  - Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer
TY  - research article
ER  -