TY - JOUR AU - Bretón-Romero, Rosa AU - Feng, Bihua AU - Holbrook, Monika AU - Farb, Melissa G AU - Fetterman, Jessica L AU - Linder, Erika A AU - Berk, Brittany D AU - Masaki, Nobuyuki AU - Weisbrod, Robert M AU - Inagaki, Elica AU - Gokce, Noyan AU - Fuster, Jose J AU - Walsh, Kenneth AU - Hamburg, Naomi M PY - 2016 DO - 10.1161/ATVBAHA.115.306578 UR - http://hdl.handle.net/20.500.12105/17497 AB - OBJECTIVEEndothelial dysfunction is linked to insulin resistance, inflammatory activation, and increased cardiovascular risk in diabetes mellitus; however, the mechanisms remain incompletely understood. Recent studies have identified proinflammatory... LA - eng PB - Lippincott Williams & Wilkins (LWW) KW - Vasodilation KW - Wnt Signaling Pathway KW - Adult KW - Aged KW - Brachial Artery KW - Case-Control Studies KW - Cells, Cultured KW - Diabetes Mellitus, Type 2 KW - Endothelial Cells KW - Endothelium, Vascular KW - Enzyme Activation KW - Female KW - Humans KW - JNK Mitogen-Activated Protein Kinases KW - Male KW - Middle Aged KW - Nitric Oxide KW - Nitric Oxide Synthase Type III KW - Oxidative Stress KW - Protein Kinase Inhibitors KW - Proto-Oncogene Proteins KW - Wnt Proteins KW - Wnt-5a Protein TI - Endothelial Dysfunction in Human Diabetes Is Mediated by Wnt5a-JNK Signaling. TY - journal article ER -