TY - JOUR AU - Montes, Marta AU - Coiras, Mayte AU - Becerra, Soraya AU - Moreno-Castro, Cristina AU - Mateos, Elena AU - Majuelos, Jara AU - Oliver, F Javier AU - Hernández-Munain, Cristina AU - Alcamí, José AU - Suñé, Carlos PY - 2015 DO - 10.1371/journal.pone.0139812 SN - 1932-6203 UR - http://hdl.handle.net/20.500.12105/6910 AB - Here, we present evidence for a specific role of the splicing-related factor TCERG1 in regulating apoptosis in live cells by modulating the alternative splicing of the apoptotic genes Bcl-x and Fas. We show that TCERG1 modulates Bcl-x alternative... LA - eng PB - Public Library of Science (PLOS) KW - Alternative Splicing KW - Apoptosis KW - Caspase 3 KW - Cytochromes c KW - HEK293 Cells KW - HeLa Cells KW - Humans KW - Jurkat Cells KW - Poly (ADP-Ribose) Polymerase-1 KW - Poly(ADP-ribose) Polymerases KW - Transcriptional Elongation Factors KW - bcl-2 Homologous Antagonist-Killer Protein KW - bcl-X Protein KW - fas Receptor TI - Functional Consequences for Apoptosis by Transcription Elongation Regulator 1 (TCERG1)-Mediated Bcl-x and Fas/CD95 Alternative Splicing TY - journal article ER -