TY - JOUR AU - Wurm, Stefanie AU - Zhang, Jisheng AU - Guinea-Viniegra, Juan AU - García, Fernando AU - Muñoz, Javier AU - Bakiri, Latifa AU - Ezhkova, Elena AU - Wagner, Erwin F AU - Munoz, Javier AU - Wagner, Erwin F. PY - 2015 DO - 10.1101/gad.249748.114 SN - 0890-9369 UR - http://hdl.handle.net/20.500.12105/10263 AB - Altered epidermal differentiation characterizes numerous skin diseases affecting >25% of the human population. Here we identified Fra-2/AP-1 as a key regulator of terminal epidermal differentiation. Epithelial-restricted, ectopic expression of Fra-2... LA - eng PB - Cold Spring Harbor Laboratory Press KW - Cell Differentiation KW - Animals KW - Cells, Cultured KW - Embryo, Mammalian KW - Enhancer of Zeste Homolog 2 Protein KW - Fos-Related Antigen-2 KW - Gene Expression Regulation, Developmental KW - Keratinocytes KW - Lysine KW - Methylation KW - Mice KW - Mitogen-Activated Protein Kinase 1 KW - Phosphorylation KW - Polycomb Repressive Complex 2 KW - Transcription Factor AP-1 TI - Terminal epidermal differentiation is regulated by the interaction of Fra-2/AP-1 with Ezh2 and ERK1/2. TY - journal article ER -