TY - GEN AU - Agusti, Alvar AU - Compte, Albert: AU - Fener, Rosa AU - Garcia-Aymerich, Judith AU - Noell, Guillaume AU - García-Cosío, Borja AU - Rodriguez-Roisin, Robert AU - Cell, Bartolome AU - Maria Anto, Josep PY - 2017 DO - 10.1371/journal.pone.0185502 SN - 1932-6203 UR - http://hdl.handle.net/20.500.12105/20460 AB - The natural history of chronic obstructive pulmonary disease (COPD) is still not well understood. Traditionally believed to be a self-inflicted disease by smoking, now we know that not all smokers develop COPD, that other inhaled pollutants different... LA - eng PB - Public Library of Science (PLOS) KW - Disease Progression KW - Dyspnea KW - Inhalation Exposure KW - Pulmonary Disease, Chronic Obstructive KW - Humans KW - Smoking KW - Computer Simulation KW - Disease Susceptibility KW - Lung KW - Male KW - Severity of Illness Index KW - Time Factors KW - Female KW - Models, Statistical KW - Smoking Cessation KW - Pulmonary Ventilation TI - The EASI model: A first integrative computational approximation to the natural history of COPD TY - research article ER -