TY - JOUR AU - Rubio-Navarro, Alfonso AU - Vázquez-Carballo, Cristina AU - Guerrero-Hue, Melania AU - García-Caballero, Cristina AU - Herencia, Carmen AU - Gutiérrez, Eduardo AU - Yuste, Claudia AU - Sevillano, Ángel AU - Praga, Manuel AU - Egea, Javier AU - Cannata, Pablo AU - Cortegano, Isabel AU - Andres, Belen de AU - Gaspar, Maria Luisa AU - Cadenas, Susana AU - Michalska, Patrycja AU - León, Rafael AU - Ortiz, Alberto AU - Egido, Jesús AU - Moreno, Juan Antonio PY - 2019 DO - 10.3389/fphar.2019.00740 SN - 1663-9812 UR - http://hdl.handle.net/20.500.12105/9174 AB - Massive intravascular hemolysis is associated with acute kidney injury (AKI). Nuclear factor erythroid-2-related factor 2 (Nrf2) plays a central role in the defense against oxidative stress by activating the expression of antioxidant proteins. We... LA - eng PB - Frontiers Media KW - Nrf2 KW - Heme KW - Hemoglobin KW - Intravascular hemolysis KW - Oxidative stress KW - Sulforaphane KW - Tubular injury TI - Nrf2 Plays a Protective Role Against Intravascular Hemolysis-Mediated Acute Kidney Injury TY - journal article ER -