TY - JOUR AU - Morando, Maria Agnese AU - Saladino, Giorgio AU - D'Amelio, Nicola AU - Pucheta-Martinez, Encarna AU - Lovera, Silvia AU - Lelli, Moreno AU - López-Méndez, Blanca AU - Marenchino, Marco AU - Campos Olivas, Ramon AU - Gervasio, Francesco Luigi PY - 2016 DO - 10.1038/srep24439 SN - 2045-2322 UR - http://hdl.handle.net/20.500.12105/8571 AB - Understanding the conformational changes associated with the binding of small ligands to their biological targets is a fascinating and meaningful question in chemistry, biology and drug discovery. One of the most studied and important is the so-called... LA - eng PB - Nature Publishing Group KW - Antineoplastic Agents KW - Imatinib Mesylate KW - Ligands KW - Magnetic Resonance Imaging KW - Molecular Conformation KW - Molecular Dynamics Simulation KW - Protein Binding KW - Surface Plasmon Resonance KW - src-Family Kinases TI - Conformational Selection and Induced Fit Mechanisms in the Binding of an Anticancer Drug to the c-Src Kinase TY - journal article ER -