TY - JOUR AU - Giganti, David AU - Yan, Kevin AU - Badilla, Carmen L. AU - Fernandez, Julio M. AU - Alegre-Cebollada, Jorge PY - 2018 DO - 10.1038/s41467-017-02528-7 SN - 2041-1723 UR - http://hdl.handle.net/20.500.12105/6695 AB - The response of titin to mechanical forces is a major determinant of the function of the heart. When placed under a pulling force, the unstructured regions of titin uncoil while its immunoglobulin (Ig) domains unfold and extend. Using single-molecule... LA - eng PB - Nature Publishing Group TI - Disulfide isomerization reactions in titin immunoglobulin domains enable a mode of protein elasticity TY - journal article ER -