TY  - JOUR
AU  - Lopez-Huertas, Maria Rosa
AU  - Li, Jasmine
AU  - Zafar, Anjum
AU  - Rodriguez‑Mora, Sara
AU  - Garcia-Dominguez, Carlota A
AU  - Mateos, Elena
AU  - Alcamí, José
AU  - Rao, Sudha
AU  - Coiras, Mayte
PY  - 2016
DO  - 10.3389/fimmu.2016.00069
SN  - 1664-3224
UR  - http://hdl.handle.net/20.500.12105/5770
AB  - PKCθ is essential for the activation of CD4(+) T cells. Upon TCR/CD28 stimulation, PKCθ is phosphorylated and migrates to the immunological synapse, inducing the activation of cellular transcription factors such as NF-κB and kinases as ERK that are...
LA  - eng
PB  - Frontiers Media
KW  - CD4+ T cell activation
KW  - HIV-1 Tat regulator
KW  - NF-kappa B
KW  - PKC theta and HIV-1 Tat interaction
KW  - PKC theta mRNA interference
KW  - Ras/Raf/MEK/Erk pathway
KW  - Nuclear colocalization
KW  - Protein kinase C theta
TI  - PKCθ and HIV-1 Transcriptional Regulator Tat Co-exist at the LTR Promoter in CD4+ T Cells
TY  - journal article
ER  -