TY - JOUR AU - Ottaviani, Silvia AU - Stebbing, Justin AU - Frampton, Adam E AU - Zagorac, Sladjana AU - Krell, Jonathan AU - de Giorgio, Alexander AU - Trabulo, Sara M AU - Nguyen, Van T M AU - Magnani, Luca AU - Feng, Hugang AU - Giovannetti, Elisa AU - Funel, Niccola AU - Gress, Thomas M AU - Jiao, Long R AU - Lombardo, Ylenia AU - Lemoine, Nicholas R AU - Heeschen, Christopher AU - Castellano, Leandro PY - 2018 DO - 10.1038/s41467-018-03962-x SN - 2041-1723 UR - http://hdl.handle.net/20.500.12105/6449 AB - TGF-β/Activin induces epithelial-to-mesenchymal transition and stemness in pancreatic ductal adenocarcinoma (PDAC). However, the microRNAs (miRNAs) regulated during this response have remained yet undetermined. Here, we show that TGF-β... LA - eng PB - Nature Publishing Group KW - CANCER STEM-CELLS KW - PANCREATIC TUMOR-GROWTH KW - MESENCHYMAL TRANSITION KW - LASER MICRODISSECTION KW - SELF-RENEWAL KW - EXPRESSION KW - MICRORNAS KW - TARGET KW - ADENOCARCINOMA KW - BIOGENESIS TI - TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression TY - journal article ER -