TY  - JOUR
AU  - Nieto-Soler, Maria
AU  - Morgado-Palacin, Isabel
AU  - Lafarga, Vanesa
AU  - Lecona, Emilio
AU  - Murga, Matilde
AU  - Callen, Elsa
AU  - Azorin, Daniel
AU  - Alonso, Javier
AU  - Lopez-Contreras, Andres J
AU  - Nussenzweig, Andre
AU  - Fernandez-Capetillo, Oscar
PY  - 2016
DO  - 10.18632/oncotarget.11643
SN  - 1949-2553
UR  - http://hdl.handle.net/20.500.12105/9615
AB  - Ewing sarcomas (ES) are pediatric bone tumors that arise from a driver translocation, most frequently EWS/FLI1. Current ES treatment involves DNA damaging agents, yet the basis for the sensitivity to these therapies remains unknown. Oncogene-induced...
LA  - eng
PB  - Impact Journals
KW  - ATR
KW  - DNA repair
KW  - Ewing sarcoma
KW  - cancer
KW  - replication stress
KW  - Animals
KW  - Antineoplastic Agents
KW  - Apoptosis
KW  - Ataxia Telangiectasia Mutated Proteins
KW  - Bone Neoplasms
KW  - Cell Line, Tumor
KW  - DNA Damage
KW  - Gene Expression Regulation, Neoplastic
KW  - Humans
KW  - Male
KW  - Mice
KW  - Mice, SCID
KW  - RNA, Small Interfering
KW  - RNA-Binding Protein EWS
KW  - Sarcoma, Ewing
TI  - Efficacy of ATR inhibitors as single agents in Ewing sarcoma
TY  - journal article
ER  -