TY  - GEN
AU  - Agra, Noelia
AU  - Cidre, Florencia
AU  - Garcia-Garcia, Laura
AU  - de la Parra, Juan
AU  - Alonso, Javier
PY  - 2010
DO  - 10.1371/journal.pone.0066281
SN  - 1932-6203
UR  - http://hdl.handle.net/20.500.12105/6487
AB  - Ewing sarcoma is the second most common bone malignancy in children and young adults. It is driven by oncogenic fusion proteins (i.e. EWS/FLI1) acting as aberrant transcription factors that upregulate and downregulate target genes, leading to cellular...
LA  - eng
PB  - Public Library of Science (PLOS)
KW  - Animals
KW  - Cell Line, Tumor
KW  - Female
KW  - Humans
KW  - Mice
KW  - Oncogene Proteins, Fusion
KW  - Protein Structure, Tertiary
KW  - Protein-Lysine 6-Oxidase
KW  - Proto-Oncogene Protein c-fli-1
KW  - RNA-Binding Protein EWS
KW  - Sarcoma, Ewing
KW  - Tumor Suppressor Proteins
KW  - Down-Regulation
TI  - Lysyl oxidase is downregulated by the EWS/FLI1 oncoprotein and its propeptide domain displays tumor supressor activities in Ewing sarcoma cells
TY  - research article
ER  -