TY  - JOUR
AU  - Paniagua, Guillen
AU  - Jacob, Harrys K C
AU  - Brehey, Oksana
AU  - García-Alonso, Sara
AU  - Pons, Tirso
AU  - Musteanu, Mónica
AU  - Drosten, Matthias
AU  - Guerra, Carmen
AU  - Barbacid, Mariano
AU  - Lechuga, Carmen G
PY  - 2022
DO  - 10.1002/1878-0261.13213
UR  - http://hdl.handle.net/20.500.12105/14701
AB  - The kinase suppressor of rat sarcoma (RAS) proteins (KSR1 and KSR2) have long been considered as scaffolding proteins required for optimal mitogen-activated protein kinase (MAPK) pathway signalling. However, recent evidence suggests that they play a...
LA  - eng
PB  - Wiley
KW  - ATP binding
KW  - KRAS(G12C)
KW  - MAPK pathway
KW  - RAS-independent proliferation
KW  - resistance
KW  - sotorasib
TI  - KSR induces RAS-independent MAPK pathway activation and modulates the efficacy of KRAS inhibitors.
TY  - journal article
ER  -