TY  - JOUR
AU  - Burgener, Anne-Valérie
AU  - Bantug, Glenn R
AU  - Meyer, Benedikt J
AU  - Higgins, Rebecca
AU  - Ghosh, Adhideb
AU  - Bignucolo, Olivier
AU  - Ma, Eric H
AU  - Loeliger, Jordan
AU  - Unterstab, Gunhild
AU  - Geigges, Marco
AU  - Steiner, Rebekah
AU  - Enamorado, Michel
AU  - Ivanek, Robert
AU  - Hunziker, Danielle
AU  - Schmidt, Alexander
AU  - Müller-Durovic, Bojana
AU  - Grählert, Jasmin
AU  - Epple, Raja
AU  - Dimeloe, Sarah
AU  - Lötscher, Jonas
AU  - Sauder, Ursula
AU  - Ebnöther, Monika
AU  - Burger, Bettina
AU  - Heijnen, Ingmar
AU  - Martínez-Cano, Sarai
AU  - Cantoni, Nathan
AU  - Brücker, Rolf
AU  - Kahlert, Christian R
AU  - Sancho, David
AU  - Jones, Russell G
AU  - Navarini, Alexander
AU  - Recher, Mike
AU  - Hess, Christoph
PY  - 2019
DO  - 10.1038/s41590-019-0482-2
UR  - http://hdl.handle.net/20.500.12105/15163
AB  - Whether screening the metabolic activity of immune cells facilitates discovery of molecular pathology remains unknown. Here we prospectively screened the extracellular acidification rate as a measure of glycolysis and the oxygen consumption rate as a...
LA  - eng
PB  - Nature Publishing Group
KW  - Anti-Inflammatory Agents
KW  - B-Lymphocytes
KW  - Cell Respiration
KW  - Cells, Cultured
KW  - Electron Transport Complex II
KW  - Fumarates
KW  - Glycolysis
KW  - Humans
KW  - Inflammation
KW  - Interleukin-6
KW  - Kelch-Like ECH-Associated Protein 1
KW  - Lymphocytosis
KW  - Mitochondria
KW  - Mutation
KW  - NF-E2-Related Factor 2
KW  - Oxygen Consumption
KW  - Prospective Studies
KW  - Signal Transduction
KW  - Whole Exome Sequencing
TI  - SDHA gain-of-function engages inflammatory mitochondrial retrograde signaling via KEAP1-Nrf2.
TY  - journal article
ER  -