TY - GEN AU - Lobo-Gonzalez, Manuel AU - Galan-Arriola, Carlos AU - Rossello, Xavier AU - González-Del-Hoyo, Maribel AU - Vilchez, Jean Paul AU - Higuero-Verdejo, María I AU - Garcia-Ruiz, Jose M AU - Lopez-Martin, Gonzalo J. AU - Sanchez-Gonzalez, Javier AU - Oliver, Eduardo AU - Pizarro, Gonzalo AU - Fuster, Valentin AU - Ibáñez, Borja PY - 2020 DO - 10.1007/s00395-020-0812-4 UR - http://hdl.handle.net/20.500.12105/10991 AB - Early metoprolol administration protects against myocardial ischemia-reperfusion injury, but its effect on infarct size progression (ischemic injury) is unknown. Eight groups of pigs (total n = 122) underwent coronary artery occlusion of varying... LA - eng PB - Springer KW - Acute myocardial infarction KW - Ischemia-reperfusion injury KW - Metoprolol KW - Early reperfusion KW - Disease Progression KW - Drug Evaluation, Preclinical KW - Myocardium KW - Magnetic Resonance Imaging KW - Myocardial Reperfusion Injury KW - Male KW - Time Factors KW - Administration, Intravenous KW - Adrenergic beta-1 Receptor Antagonists KW - Cardiac Imaging Techniques KW - Metoprolol KW - Animals KW - ST Elevation Myocardial Infarction KW - Swine TI - Metoprolol blunts the time-dependent progression of infarct size TY - research article ER -