TY - GEN AU - Concha, Emilio G. de la AU - Cavanillas, María L. AU - Cénit, M. Carmen AU - Urcelay, Elena AU - Arroyo, Rafael AU - Fernández, Óscar AU - Álvarez-Cermeño, José C. AU - Leyva, Laura AU - Villar, Luisa M. AU - Núñez, Concepción PY - 2012 DO - 10.1371/journal.pone.0031018 UR - http://hdl.handle.net/20.500.12105/17035 AB - BACKGROUND: Multiple sclerosis (MS) is a multifactorial disease with a genetic basis. The strongest associations with the disease lie in the Human Leukocyte Antigen (HLA) region. However, except for the DRB1*15:01 allele, the main risk factor... LA - eng PB - Public Library of Science (PLOS) KW - HLA-DRB1*03:01 antigen KW - Antigeno HLA-DRB1*03:01 KW - Estudios caso-control KW - Estudios de asociación genética KW - Predisposición genética a la enfermedad KW - Cadenas HLA-DRB1 KW - Haplotipos KW - Humanos KW - Inmunoglobulina M KW - Esclerosis Múltiple KW - Factores de riesgo KW - Case-Control Studies KW - Genetic Predisposition to Disease KW - HLA-DRB1 Chains KW - Haplotypes KW - Humans KW - Immunoglobulin M KW - Multiple Sclerosis KW - Risk Factors KW - Genetic Association Studies TI - DRB1*03:01 haplotypes: differential contribution to multiple sclerosis risk and specific association with the presence of intrathecal IgM bands. TY - research article ER -