TY - GEN AU - Herranz, Daniel AU - Muñoz-Martin, Maribel AU - Cañamero, Marta AU - Mulero, Francisca AU - Martinez-Pastor, Barbara AU - Fernandez-Capetillo, Oscar AU - Serrano, Manuel PY - 2010 UR - https://hdl.handle.net/20.500.12105/26212 AB - Genetic overexpression of protein deacetylase Sir2 increases longevity in a variety of lower organisms, and this has prompted interest in the effects of its closest mammalian homologue, Sirt1, on ageing and cancer. We have generated transgenic mice... LA - eng PB - Nature Publishing Group KW - SMALL-MOLECULE ACTIVATORS KW - CALORIC RESTRICTION KW - LIFE-SPAN KW - RESVERATROLS KW - TUMORIGENESIS KW - SURVIVAL KW - MICE KW - EXPRESSION KW - SIRTUIN KW - DIET TI - Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer. TY - research article ER -