TY - GEN AU - Nieto, Patricia AU - Ambrogio, Chiara AU - Esteban-Burgos, Laura AU - Gómez-López, Gonzalo AU - Blasco, María Teresa AU - Yao, Zhan AU - Marais, Richard AU - Rosen, Neal AU - Chiarle, Roberto AU - Pisano, David G AU - Barbacid, Mariano AU - Santamaría, David AU - Nieto, Patricia AU - Ambrogio, Chiara AU - Esteban-Burgos, Laura AU - Gómez-López, Gonzalo AU - Blasco, María Teresa AU - Yao, Zhan AU - Marais, Richard AU - Rosen, Neal AU - Chiarle, Roberto AU - Pisano, David G AU - Santamaría, David PY - 2017 UR - https://hdl.handle.net/20.500.12105/25313 AB - The initiating oncogenic event in almost half of human lung adenocarcinomas is still unknown, a fact that complicates the development of selective targeted therapies. Yet these tumours harbour a number of alterations without obvious oncogenic function... LA - eng PB - Nature Publishing Group KW - TUMOR-SUPPRESSOR ACTIVITY KW - K-RAS ONCOGENE KW - MOUSE MODEL KW - C-RAF KW - B-RAF KW - CANCER KW - CELLS KW - PROTEIN KW - PROGRESSION KW - INHIBITORS TI - A Braf kinase-inactive mutant induces lung adenocarcinoma. TY - research article ER -