TY - GEN AU - Maiques-Diaz, A AU - Chou, F S AU - Wunderlich, M AU - Gómez-López, G AU - Jacinto, F V AU - Rodriguez Perales, Sandra AU - Larrayoz, M J AU - Calasanz, M J AU - Mulloy, J C AU - Cigudosa, J C AU - Alvarez, S PY - 2012 UR - https://hdl.handle.net/20.500.12105/26180 AB - The AML1-ETO fusion protein, which is present in 10-15% of cases of acute myeloid leukemia, is known to repress myeloid differentiation genes through DNA binding and recruitment of chromatin-modifying proteins and transcription factors in target... LA - eng PB - Nature Publishing Group KW - AML1-ETO KW - myeloid leukemia KW - histone deacetylation KW - H3K9me3 KW - SP1 TI - Chromatin modifications induced by the AML1-ETO fusion protein reversibly silence its genomic targets through AML1 and Sp1 binding motifs. TY - research article ER -