TY - JOUR AU - Leandro-García, Luis J AU - Leskelä, Susanna AU - Inglada-Pérez, Lucía AU - Landa, Iñigo AU - de Cubas, Aguirre A AU - Maliszewska, Agnieszka AU - Comino-Méndez, Iñaki AU - Letón, Rocío AU - Gómez-Graña, Álvaro AU - Torres, Raúl AU - Ramírez, Juan Carlos AU - Álvarez, Sara AU - Rivera, José AU - Martínez, Constantino AU - Lozano, María Luisa AU - Cascón, Alberto AU - Robledo Batanero, Mercedes AU - Rodriguez Antona, Cristina PY - 2012 DO - 10.1158/0008-5472.CAN-11-2861 UR - http://hdl.handle.net/20.500.12105/17499 AB - Cellular microtubules composed of α-β-tubulin heterodimers that are essential for cell shape, division, and intracellular transport are valid targets for anticancer therapy. However, not all the conserved but differentially expressed members of the... LA - eng PB - American Association for Cancer Research (AACR) KW - Antineoplastic Agents KW - Genetic Predisposition to Disease KW - Genotype KW - Humans KW - Microtubules KW - Paclitaxel KW - Polymorphism, Single Nucleotide KW - Protein Isoforms KW - Reverse Transcriptase Polymerase Chain Reaction KW - Thrombocytopenia KW - Tubulin TI - Hematologic β-tubulin VI isoform exhibits genetic variability that influences paclitaxel toxicity. TY - journal article ER -