TY - GEN AU - Fisher, Benjamin A AU - Cartwright, Alison J AU - Quirke, Anne-Marie AU - de Pablo, Paola AU - Romaguera, Dora AU - Panico, Salvatore AU - Mattiello, Amalia AU - Gavrila, Diana AU - Navarro, Carmen AU - Sacerdote, Carlotta AU - Vineis, Paolo AU - Tumino, Rosario AU - Lappin, David F AU - Apazidou, Danae AU - Culshaw, Shauna AU - Potempa, Jan AU - Michaud, Dominique S AU - Riboli, Elio AU - Venables, Patrick J PY - 2015 DO - 10.1186/s12891-015-0792-y SN - 1471-2474 UR - http://hdl.handle.net/20.500.12105/20158 AB - Background: Antibodies to citrullinated proteins (ACPA) occur years before RA diagnosis. Porphyromonas gingivalis expresses its own peptidylarginine deiminase (PPAD), and is a proposed aetiological factor for the ACPA response. Smoking is a risk... LA - eng PB - BioMed Central (BMC) KW - Smoking KW - Rheumatoid arthritis (RA) KW - Anti-citrullinated protein antibodies (ACPA) KW - Porphyromonas gingivalis KW - Citrullination KW - Autoantigens KW - Case-Control Studies KW - Cysteine Endopeptidases KW - Adult KW - Periodontitis KW - Humans KW - Hydrolases KW - Smoking KW - Middle Aged KW - Protein-Arginine Deiminases KW - Adhesins, Bacterial KW - Male KW - Peptides, Cyclic KW - Prospective Studies KW - Arthritis, Rheumatoid KW - Europe KW - Porphyromonas gingivalis KW - Female TI - Smoking, Porphyromonas gingivalis and the immune response to citrullinated autoantigens before the clinical onset of rheumatoid arthritis in a Southern European nested case-control study TY - research article ER -