TY - JOUR AU - Martín-Saavedra, Francisco M AU - González-García, Coral AU - Bravo, Beatriz AU - Ballester, Sara PY - 2008 DO - 10.1016/j.molimm.2008.06.006 SN - 0161-5890 UR - http://hdl.handle.net/20.500.12105/15504 AB - Beta-interferon (IFN-beta) is a valuable therapy for multiple sclerosis (MS) which is also effective in the animal model of experimental autoimmune encephalomyelitis (EAE). However, the accurate mechanisms to explain its anti-inflammatory activity in... LA - eng PB - Elsevier KW - EAE KW - IL-4 KW - IL-17 KW - Foxp3 KW - nTreg KW - IFN-Beta KW - Animals KW - CD4-Positive T-Lymphocytes KW - Cell Differentiation KW - Cells, Cultured KW - Interferon-beta KW - Interleukin-17 KW - Mice KW - Mice, Inbred C3H KW - Spleen KW - T-Lymphocytes, Regulatory KW - Th2 Cells TI - Beta interferon restricts the inflammatory potential of CD4+ cells through the boost of the Th2 phenotype, the inhibition of Th17 response and the prevalence of naturally occurring T regulatory cells TY - journal article ER -