TY  - JOUR
AU  - Estrada, Juan C
AU  - Torres, Yaima
AU  - Benguria, Alberto
AU  - Dopazo, Ana
AU  - Roche, E
AU  - Carrera-Quintanar, L
AU  - Pérez, R A
AU  - Enriquez, Jose Antonio
AU  - Torres-Ruiz, Raul
AU  - Ramirez, Juan Carlos
AU  - Samper, Enrique
AU  - Bernad, Antonio
PY  - 2013
DO  - 10.1038/cddis.2013.211
SN  - 2041-4889
UR  - http://hdl.handle.net/20.500.12105/7586
AB  - In most clinical trials, human mesenchymal stem cells (hMSCs) are expanded in vitro before implantation. The genetic stability of human stem cells is critical for their clinical use. However, the relationship between stem-cell expansion and genetic...
LA  - eng
KW  - Cell Cycle Proteins
KW  - Cell Proliferation
KW  - Cells, Cultured
KW  - Chemokine CXCL12
KW  - Gelsolin
KW  - Gene Expression
KW  - Gene Expression Regulation
KW  - Genomic Instability
KW  - Humans
KW  - Mesenchymal Stem Cells
KW  - Oxygen Consumption
KW  - Reactive Oxygen Species
KW  - Telomerase
KW  - Telomere Homeostasis
KW  - Aneuploidy
KW  - Cellular Senescence
KW  - Oxidative Stress
TI  - Human mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy
TY  - journal article
ER  -