TY - GEN AU - Santos, C AU - Azuara, D AU - Vieitez, JM AU - Paez, D AU - Falcó, Esther AU - Elez, Elena AU - Lopez-Lopez, C AU - Valladares, M AU - Robles-Diaz, L AU - Garcia-Alfonso, P AU - Buges, C AU - Duran, Gema AU - Salud, A AU - Navarro, V AU - Capella, G AU - Aranda, E AU - Salazar, R AU - Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) PY - 2019 DO - 10.1093/annonc/mdz082 SN - 0923-7534 UR - https://hdl.handle.net/20.500.12105/22782 AB - Background: Several studies show the importance of accurately quantifying not only KRAS and other low-abundant mutations because benefits of anti-EGFR therapies may depend on certain sensitivity thresholds. We assessed whether ultra-selection of... LA - eng PB - Oxford University Press KW - Digital PCR KW - FOLFIRI KW - Metastatic colorectal cancer KW - Panitumumab KW - Patient selection KW - PCR TI - Phase II study of high-sensitivity genotyping of KRAS, NRAS, BRAF and PIK3CA to ultra-select metastatic colorectal cancer patients for panitumumab plus FOLFIRI: the ULTRA trial TY - research article ER -