TY - GEN AU - Villanueva-Paz, Marina AU - Niu, Hao AU - Segovia-Zafra, Antonio AU - Medina-Caliz, Inmaculada AU - Sanabria-Cabrera, Judith AU - Lucena, M. Isabel AU - Andrade, Raúl J. AU - Alvarez-Alvarez, Ismael PY - 2021 DO - 10.3390/jcm10225317 UR - http://hdl.handle.net/20.500.12105/18501 AB - Drug-induced liver injury (DILI) encompasses the unexpected damage that drugs can cause to the liver. DILI may develop in the context of an immunoallergic syndrome with cutaneous manifestations, which are sometimes severe (SCARs). Nevirapine,... LA - eng PB - Multidisciplinary Digital Publishing Institute (MDPI) KW - Drug-induced liver injury KW - Severe cutaneous adverse reactions KW - Hypersensitivity KW - Gaps KW - Causality assessment KW - Diagnosis KW - Management KW - Clinical trial KW - Immune response KW - Enfermedad hepática inducida por sustancias y drogas KW - Hipersensibilidad KW - Relaciones intergeneracionales KW - Diagnóstico KW - Ensayo clínico KW - Inmunidad KW - Allopurinol KW - Nevirapine KW - Alleles KW - Cicatrix KW - HLA-B Antigens KW - HLA-A Antigens KW - Prognosis KW - Sulfonamides KW - Anti-Bacterial Agents KW - Pharmaceutical Preparations, Dental TI - Critical Review of Gaps in the Diagnosis and Management of Drug-Induced Liver Injury Associated with Severe Cutaneous Adverse Reactions TY - review article ER -