TY  - JOUR
AU  - Marina-Zarate, Ester
AU  - Perez-Garcia, Arantxa
AU  - Ramiro, Almudena R
PY  - 2017
DO  - 10.3389/fimmu.2017.01076
SN  - 1664-3224
UR  - http://hdl.handle.net/20.500.12105/5186
AB  - In response to antigenic stimulation B cells undergo class switchrecombination (CSR) at the immunoglobulin heavy chain (IgH) to replacethe primary IgM/IgD isotypes by IgG, IgE, or IgA. CSR is initiated byactivation-induced cytidine deaminase (AID)...
LA  - eng
PB  - Frontiers Media
KW  - Class switch recombination
KW  - CCCTC-binding factor
KW  - Germline transcription
KW  - Activation-induced deaminase
KW  - Somatic hypermutation
KW  - ACTIVATION-INDUCED DEAMINASE
KW  - S-MU REGION
KW  - SOMATIC HYPERMUTATION
KW  - V(D)JRECOMBINATION
KW  - FACTOR CTCF
KW  - B-CELLS
KW  - LOCUS
KW  - ELEMENTS
KW  - AID
KW  - GENES
TI  - CCCTC-Binding Factor Locks Premature IgH Germline Transcription andRestrains Class Switch Recombination
TY  - journal article
ER  -